Introduction

Fentalogs – Pharmacology, Toxicology & Analytical Approaches

Fentalogs – Pharmacology, Toxicology & Analytical Approaches

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Overview

We will review the chemistry of fentanyl, its analogs and precursors, their pharmacology and relative potency, and approaches to identifying novel fentanyl analogs in forensic toxicology casework.

Fentanyl and its analogs, sometimes called “The Fentalogs”, are among the most dangerous of the novel psychoactive substances, and create significant challenges to forensic toxicologists in being able to recognize and definitively identify them, quantify them and interpret these results. Maintenance of a current and relevant scope of testing in death investigation casework is a critical process in being able to certify drug related deaths, and to use that information for threat assessment, harm reduction and drug interdiction. This webinar will review the structural families of the fentanyl analogs, and aspects of their chemistry that assists in their detection and identification. Additionally, we will describe analytical methods for the screening and confirmation of fentanyl and its analogs, considerations about methods and detection limits, the challenges of separating close structural isomers, and the interpretation of toxicological results for priority fentanyl derived drugs and their metabolites, including fentanyl, nor fentanyl, 4-ANPP, Acetylfentanyl, Carfentanil, Butyrylfentanyl, Furanylfentanyl, 3-methyl fentanyl, and emerging related compounds.

A certificate of completion is available for all who register and attend this webinar.

Presenter

  • Dr. Barry Logan

Funding for this Forensic Technology Center of Excellence webinar has been provided by the National Institute of Justice, Office of Justice Programs, U.S. Department of Justice.

The opinions, findings, and conclusions or recommendations expressed in this webinar are those of the presenter(s) and do not necessarily reflect those of the U.S. Department of Justice.

Contact us at ForensicCOE@rti.org with any questions and subscribe to our newsletter for notifications.


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